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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary items found
Status Description Section
REDDimethyl fumarate 120mg & 240mg Tecfidera®
(Capsules) 		Malignant disease and immunosuppression, Other immunomodulating drugs, 08.02.04
REDDimethyl fumarate 30mg, 120mg Skilarence®
(Tablets) 		Skin, Drugs affecting the immune response, 13.05.03
Non Formulary items found
Status Description Section
 DIMETHYL SULFOXIDE  Unlicensed Medicines / Significant off-label use, Unlicensed Medicines, 20
 Idoxuridine in Dimethyl Sulfoxide Herpid® Skin, Antiviral preparations, 13.10.03
 Polydimethylsiloxane  Unlicensed Medicines / Significant off-label use, Unlicensed Medicines, 20
Searchiing the National BNF we found these items - Click button under Local to search local formulary or BNF to view on online BNF.
Local BNF Section
Dimethyl  Dimethyl Fumarate Immune System, Immunosuppressants, Immunomodulating Drugs
Immune System Disorders And Transplantation, Multiple Sclerosis
Dimethyl  Dimethyl Fumarate Skin, Immunosuppressants, Immunomodulating Drugs
Inflammatory Skin Conditions, Eczema And Psoriasis
Selecting a button in the local column will search the local formulary again for the word on the button. Where the button is in outline no local match at drug name level was found.
Links found
MHRA Drug Safety Update (April 2016) - Dimethyl fumarate (Tecfidera): updated advice on risk of progressive multifocal leukoencephalopathy
MHRA Drug Safety Update (January 2021): Dimethyl fumarate (Tecfidera): updated advice on the risk of progressive multifocal leukoencephalopathy (PML) associated with mild lymphopenia
NICE TA320: Dimethyl fumarate for treating relapsing‑remitting multiple sclerosis
NICE TA475: Dimethyl fumarate for treating moderate to severe plaque psoriasis