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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary items found
Status Description Section
REDIvacaftor tablets Kalydeco® Respiratory system, Mucolytics, 03.07
REDlumacaftor–ivacaftor tablets Orkambi® Respiratory system, Mucolytics, 03.07
REDtezacaftor–ivacaftor tablets Symkevi® Respiratory system, Mucolytics, 03.07
REDIvacaftor, tezacaftor, elexacaftor 75 mg/50 mg/100 mg film-coated tablets Kaftrio® Respiratory system, Mucolytics, 03.07
REDVanzacaftor-tezacaftor-deutivacaftor Alyftrek® Respiratory system, Mucolytics, 03.07
Searchiing the National BNF we found these items - Click button under Local to search local formulary or BNF to view on online BNF.
Local BNF Section
Deutivacaftor Deutivacaftor With Tezacaftor And Vanzacaftor Respiratory System, Mucolytics
Conditions Affecting Sputum Viscosity, Cystic Fibrosis
Ivacaftor  Ivacaftor With Tezacaftor And Elexacaftor Respiratory System, Mucolytics
Conditions Affecting Sputum Viscosity, Cystic Fibrosis
Selecting a button in the local column will search the local formulary again for the word on the button. Where the button is in outline no local match at drug name level was found.
Links found
MHRA DSU Feb 2022: Ivacaftor, tezacaftor, elexacaftor (Kaftrio▼) in combination with ivacaftor (Kalydeco): risk of serious liver injury; updated advice on liver function testing
NICE TA1085: Vanzacaftor-tezacaftor-deutivacaftor for treating cystic fibrosis with 1 or more F508del mutations in the CFTR gene in people 6 years and over
NICE TA988 Evidence-based recommendations on ivacaftor–tezacaftor–elexacaftor (Kaftrio) plus ivacaftor (Kalydeco), tezacaftor–ivacaftor (Symkevi) plus ivacaftor, and lumacaftor–ivacaftor (Orkambi) for treating cystic fibrosis.