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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary items found
Status Description Section
GREENClindamycin/ tretinoin Treclin®
(Gel) 		Skin, Topical antibacterials for acne, 13.06.01
REDTretinoin 10mg
(Capsules) 		Malignant disease and immunosuppression, Other antineoplastic drugs, 08.01.05
REDAlitretinoin Toctino® Skin, Preparations for eczema, 13.05.01
REDIsotretinoin  Skin, Oral retinoid for acne, 13.06.02
Non Formulary items found
Status Description Section
 Isotretinoin with erythromycin Isotrexin®
(Gel) 		Skin, Topical retinoids and related preparations for acne, 13.06.01
 Tretinoin with antibacterial Aknemycin® Plus Skin, Topical retinoids and related preparations for acne, 13.06.01
 Isotretinoin Isotrex® gel Skin, Topical retinoids and related preparations for acne, 13.06.01
Searchiing the National BNF we found these items - Click button under Local to search local formulary or BNF to view on online BNF.
Local BNF Section
Tretinoin  Tretinoin [Specialist Drug] Malignant Disease, Retinoid And Related Drugs
Cytotoxic Responsive Malignancy
Tretinoin  Tretinoin With Clindamycin Skin, Antibacterials, Lincosamides
Rosacea And Acne, Acne
Tretinoin  Tretinoin With Clindamycin Skin, Retinoid And Related Drugs
Rosacea And Acne, Acne
Tretinoin  Tretinoin With Erythromycin Skin, Antibacterials, Macrolides
Rosacea And Acne, Acne
Tretinoin  Tretinoin With Erythromycin Skin, Retinoid And Related Drugs
Rosacea And Acne, Acne
Selecting a button in the local column will search the local formulary again for the word on the button. Where the button is in outline no local match at drug name level was found.
Links found
DSU Oct 2017: Isotretinoin (Roaccutane): rare reports of erectile dysfunction and decreased libido
MHRA Drug Safety Update (December 2014) - Isotretinoin (Roaccutane): reminder of possible risk of psychiatric disorders
MHRA Drug Safety Update: Isotretinoin (Roaccutane¥): reminder of important risks and precautions (August 2020)
MHRA DSU April 2023 - Isotretinoin (Roaccutane▼): new safety measures to be introduced in the coming months, including additional oversight on initiation of treatment for patients under 18 years
MHRA DSU Jan 2026: Isotretinoin – changes to prescribing guidance and additional risk minimisation measures
MHRA DSU Oct 2023 Isotretinoin (Roaccutane▼): introduction of new safety measures, including additional oversight of the initiation of treatment for patients under 18 years of age
NICE TA177: Eczema (chronic) - alitretinoin