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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary Chapter: 25 - A2 - Borderline substances 
Links:
BLMK ICB Guidance: Infant Formula
A2.05.01 Special additives for conditions of intolerance

Probiotics (Labinic®)
(Oral drops)

RED
Restricted Drug Restricted

Neonatal unit only:  for the prevention of necrotising enterocolitis (NEC) in high risk pre-term infants (as per approved guideline). This is not a licensed medicine, it is classed as a food supplement.

BNF BNFc SPC

Probiotics (Vivomixx Neo®)

RED
Restricted Drug Restricted

For patients at HIGH risk of developing C.difficile associated diarrhoea (CDAD) receiving broad spectrum antibiotics, according to attached Bedfordshire Hospital Trust protocol.

Start at the same time as broad spectrum antibiotics and continue for 7 days after stopping. Prescribe the whole course on discharge.

Brand change to Vivomixx Neo (Vivomixx discontinued)

Updated: May 2025

BNF BNFc SPC
Non formulary items

Colief®

 
Non Formulary
BNF BNFc SPC

Fructose

 
Non Formulary
BNF BNFc SPC
Classifications
GREEN
May be initiated in any care setting
Amber SPA
Specialist to advise therapy and provide first 28 days supply, continuation in Primary Care
Amber SPIS
Specialist to initiate and stabilise medicine prior to continuation in Primary Care
SCG
To be prescribed as per Shared Care Guidance. If no SCG in place status reverts to red.
RED
Red medicines are designated as specialist only medicines which should only be prescribed by a specialist, usually within secondary care (either due to the requirement for specialist knowledge, long-term monitoring requirements, or restrictions that mean medicine supplies are only available to hospitals).
DNP
A decision has been made either locally and/or nationally not to routinely commission this preparation. Do not prescribe.
SELF
To be purchased over the counter. May be prescribed for chronic, long term conditions or on admission to hospital if essential.