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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary Chapter: 4 - Central nervous system 
Notes:

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing
04.02.01 Antipsychotic Drugs
NICE CG103: Delirium NICE CG178: Schizophrenia

Chlorpromazine

Amber SPA
Formulary
25mg, 50mg & 100mg Tablets
25mg/5mL Syrup
100mg/5mL Syrup
BNF BNFc SPC

Chlorpromazine

RED
Formulary
50mg/2mL Injection
BNF BNFc SPC

Haloperidol
(Oral)

GREEN
Formulary
  • 1.5mg, 5mg & 10mg Tablets
  • 10mg/5mL & 5mg/5mL oral solution

Note: Do not prescribe 500microgram tablets due to high cost - instead consider using oral solution.

NB: 500microgram Capsules discontinued

Entry reviewed: February 2025

BNF BNFc SPC
MHRA DSU Dec 2020: reminder of risks when used in elderly patients for the acute treatment of delirium

Haloperidol 5mg/1mL
(Injection)

GREEN
Formulary

NOTE: Intravenous use is now an unlicensed use. All IV use restricted to Critical Care areas only.

Initiation in Primary Care for palliative care only

BNF BNFc SPC
MHRA DSU Dec 2021: reminder of risks when used in elderly patients for the acute treatment of delirium

Levomepromazine
(Oral)

GREEN
Formulary

25mg Tablets

Initiation in Primary Care for palliative care only

The tablets can be dispersed in water for administration if necessary

 

Entry reviewed: March 2024

BNF BNFc SPC

Benperidol (Anquil®)

RED
Restricted Drug Restricted

For intitation and prescribing by ELFT Specialists only

BNF BNFc SPC

Levomepromazine
(Injection)

GREEN
Formulary

25mg/1mL Injection

Initiation in Primary Care for palliative care only

BNF BNFc SPC

Pericyazine
(Tablets)

RED
Restricted Drug Restricted

Restricted use in Mental Health Trusts

BNF BNFc SPC

Pimozide
(Tablets)

RED
Restricted Drug Restricted

For restricted use in Mental Health Trust

BNF BNFc SPC

Sulpiride

Amber SPA
Formulary

200mg Tablets

BNF BNFc SPC

Trifluoperazine

Amber SPA
Formulary

1mg & 5mg Tablets

N.B. Price increase, now very expensive.

For initiation by Mental Health specialist from ELFT only

BNF BNFc SPC

Zuclopenthixol

Amber SPA
Formulary
2mg & 10mg Tablets
BNF BNFc SPC

Zuclopenthixol 50mg/1mL, 200mg/1mL (Clopixol Acuphase®)
(Injection (oily))

RED
Restricted Drug Restricted
See Section 04.02.02 for depot preparations

Restricted - initiation by Consultant Psychiatrist (Mental Health Trust) only.
IMPORTANT NOTE:- when prescribing, dispensing or administering, check that this is the correct preparation - this preparation is usually used in hospital for an acute episode and should not be confused with depot preparations which are usually used in the community or clinics for maintenance treatment.
BNF BNFc SPC
04.02.01 First-Generation Antipsychotic Drugs
04.02.01 Second-Generation Antipsychotic Drugs
Classifications
GREEN
May be initiated in any care setting
Amber SPA
Specialist to advise therapy and provide first 28 days supply, continuation in Primary Care
Amber SPIS
Specialist to initiate and stabilise medicine prior to continuation in Primary Care
SCG
To be prescribed as per Shared Care Guidance. If no SCG in place status reverts to red.
RED
Red medicines are designated as specialist only medicines which should only be prescribed by a specialist, usually within secondary care (either due to the requirement for specialist knowledge, long-term monitoring requirements, or restrictions that mean medicine supplies are only available to hospitals).
DNP
A decision has been made either locally and/or nationally not to routinely commission this preparation. Do not prescribe.
SELF
To be purchased over the counter. May be prescribed for chronic, long term conditions or on admission to hospital if essential.