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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary Chapter: 6 - Endocrine system 
Notes:

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing
06.05.01 Hypothalamic and anterior pituitary hormones and anti-oestrogens
06.05.01 Anti-oestrogens
06.05.01 Anterior pituitary hormones

Choriogonadotropin alfa 250mcg (Ovitrelle®)
(Injection)

RED
Restricted Drug Restricted

For Fertility clinic only.

N.B. 250micrograms is equivalent to approximately 6500units

BNF BNFc SPC

Menotrophin
(Injection)

RED
Restricted Drug Restricted

Also called Human Menopausal Gonadotrophins.

Contracted brands include Menopur and Meriofert. 75 units/vial can be ordered for use in hospital.

For outpatient prescribing there is a multidose vial containing 1200 units/vial and presentation inlcudes alcohol wipes, needles and disposable graduated syringes.

BNF BNFc SPC

Pegvisomant (Somavert®)
(Injection)

RED
Restricted Drug Restricted

PbR excluded - funding approval required.

Funded by NHS England.

BNF BNFc SPC

Somapacitan (Sogroya®)
(10 mg/1.5 mL & 15 mg/1.5 mL solution for injection in pre-filled pen)

RED
Restricted Drug Restricted

FOR ALL PRESCRIBING – Blueteq or High cost drug form required – see link from Formulary homepage.

Restricted for use in accordance with the following NICE TA(s):

BNF BNFc SPC
NICE TA1066: Somapacitan for treating growth hormone deficiency in people 3 to 17 years

Somatrogon (Ngenla®)
(24mg and 60mg solution for injection in pre filled pen)

RED
Restricted Drug Restricted

FOR ALL PRESCRIBING – Blueteq or High cost drug form required – see link from Formulary homepage.

Restricted for use in accordance with the following NICE TA(s):

BNF BNFc SPC
NICE TA863: Somatrogon for treating growth disturbance in children and young people aged 3 years and over

Somatropin

Amber SPA
Restricted Drug Restricted

Restricted - prescribing by Consultant Endocrinologists or Paediatricians only, in accordance with NICE TA64 or NICE TA188.

Several different brands are available, to avoid switching between brands it is recommended to prescribe by brand name.

Preparations as agreed in PAC Policy (Please see the link below)

 

 

Red Norditropin FlexPro and NordiFlex pre-filled pen brands are restricted to secondary care (no GP prescribing).

How to recycle pens using PenCycle®

 

Norditropin SimpleXx has been discontinued (Oct 222)

 

Entry Reviewed: November 2022

BNF BNFc SPC
Human Growth Hormone (Somatropin) Prescribing Support JPC Bulletin 233 (Nov 18): Recommendations on the use of growth hormone devices in children NICE TA188: Human growth hormone (somatropin) for the treatment of growth failure in children (review) NICE TA64: Growth hormone deficiency (adults) - human growth hormone

Tetracosactide (Synacthen®)

RED
Formulary
250microgram/1mL Injection
BNF BNFc SPC

Chorionic Gonadotrophin

RED
Restricted Drug Restricted

unlicensed unlicensed

N.B. Pregnyl has now been discontinued.

Available as an unlicensed product in 3 strengths: 2000units, 1500units & 5000units.

BNF BNFc SPC
06.05.01 Hypothalmic hormones
Classifications
GREEN
May be initiated in any care setting
Amber SPA
Specialist to advise therapy and provide first 28 days supply, continuation in Primary Care
Amber SPIS
Specialist to initiate and stabilise medicine prior to continuation in Primary Care
SCG
To be prescribed as per Shared Care Guidance. If no SCG in place status reverts to red.
RED
Red medicines are designated as specialist only medicines which should only be prescribed by a specialist, usually within secondary care (either due to the requirement for specialist knowledge, long-term monitoring requirements, or restrictions that mean medicine supplies are only available to hospitals).
DNP
A decision has been made either locally and/or nationally not to routinely commission this preparation. Do not prescribe.
SELF
To be purchased over the counter. May be prescribed for chronic, long term conditions or on admission to hospital if essential.