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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary Chapter: 7 - Obstetrics, Gynaecology, and urinary-tract disorders 
Notes:

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing

07.03.02.02 Parenteral progestogen-only contraceptives

Medroxyprogesterone Acetate (Depo-Provera®)
(150 mg/ml intramuscular injection, prefilled syringe)

Formulary

Long acting reversible contraception

13 Weekly intramuscular injection (FSRH recommendation, Off label use)

Associated with small loss of bone mineral density (BMD), which is usually recovered after discontinuation. Risks and benefits should be re-assessed every 2 years.

Entry reviewed: September 2024.

Medroxyprogesterone acetate (Sayana Press®)
(104mg/0.65ml subcutaneous injection)

Formulary

Long acting reversible contraception.

13 Weekly subcutaneous Injection

Women can self-administer after adequate training. Women wishing to do so can be referred to Sexual Health services for training.

Associated with small loss of bone mineral density (BMD), which is usually recovered after discontinuation. Risks and benefits should be re-assessed every 2 years.

Entry reviewed September 2024.

Classifications
May be initiated in any care setting
Specialist to advise therapy and provide first 28 days supply, continuation in Primary Care
Specialist to initiate and stabilise medicine prior to continuation in Primary Care
To be prescribed as per Shared Care Guidance. If no SCG in place status reverts to red.
Red medicines are designated as specialist only medicines which should only be prescribed by a specialist, usually within secondary care (either due to the requirement for specialist knowledge, long-term monitoring requirements, or restrictions that mean medicine supplies are only available to hospitals).
A decision has been made either locally and/or nationally not to routinely commission this preparation. Do not prescribe.
To be purchased over the counter. May be prescribed for chronic, long term conditions or on admission to hospital if essential.