NHS Logo
Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary Chapter: 8 - Malignant disease and immunosuppression 
Notes:

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing
08.01 Cytotoxic drugs
08.01 Side-effects of cytotoxic drugs
08.01 Drugs for cytotoxic-induced side-effects

Anhydrous sodium thiosulfate (Pedmarqsi®)
(80 mg/mL solution for infusion)

RED
Restricted Drug Restricted

RESTRICTED FOR ALL PRESCRIBING - Blueteq or High cost drug form required - see link from Formulary homepage.

For use in accordance with the following NICE TA(s) only:

BNF BNFc SPC
NICE TA1034: Anhydrous sodium thiosulfate for preventing hearing loss caused by cisplatin chemotherapy in people 1 month to 17 years with localised solid tumours

Calcium Folinate

RED
Restricted Drug Restricted
15mg Tablets
30mg/10mL Injection
100mg/10mL & 300mg/30mL Injection Solution

BNF BNFc SPC

Mesna

RED
Formulary
400mg Tablets
1g/10mL Injection
BNF BNFc SPC

Uridine Triacetate (Vistogard®)
(10g Oral Granules)

RED
Restricted Drug Restricted

For the treatment of patients exhibiting early-onset severe toxicities following 5-fluorouracil or capecitabine administration in line with the NHSE Clinical Commissioning Policy.

Blueteq required prior to use.

BNF BNFc SPC BlueTeq
Clinical Commissioning Urgent Policy Statement: Uridine triacetate for the treatment of patients exhibiting earlyonset severe toxicities following 5-fluorouracil or capecitabine administration (all ages) NHS England Clinical Commissioning Urgent Policy Statement
Classifications
GREEN
May be initiated in any care setting
Amber SPA
Specialist to advise therapy and provide first 28 days supply, continuation in Primary Care
Amber SPIS
Specialist to initiate and stabilise medicine prior to continuation in Primary Care
SCG
To be prescribed as per Shared Care Guidance. If no SCG in place status reverts to red.
RED
Red medicines are designated as specialist only medicines which should only be prescribed by a specialist, usually within secondary care (either due to the requirement for specialist knowledge, long-term monitoring requirements, or restrictions that mean medicine supplies are only available to hospitals).
DNP
A decision has been made either locally and/or nationally not to routinely commission this preparation. Do not prescribe.
SELF
To be purchased over the counter. May be prescribed for chronic, long term conditions or on admission to hospital if essential.