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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary Chapter: 8 - Malignant disease and immunosuppression 
Notes:

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing

08.01.05 Other antineoplastic drugs
08.01.05 Amsacrine
08.01.05 Arsenic trioxide
08.01.05 Bevacizumab
08.01.05 Bexarotene
08.01.05 Bortezomib
08.01.05 Brentuximab vedotin
08.01.05 Cetuximab
08.01.05 Crisantaspase
08.01.05 Dacarbazine and Temozolomide
08.01.05 Erlotinib
08.01.05 Hydroxycarbamide

Hydroxycarbamide 500mg capsules (generic or Hydrea®)
(Oncology indications)

RED
Formulary

Licensed for chronic myeloid leukaemia (CML) in the chronic or accelerated phase of the disease

 

Hydrea® is a cost-effective brand licensed for the treatment of:

  • Chronic myeloid leukaemia:

            -as pre-TKI treatment phase before confirmation of BCR-ABL fusion with an immediate need               for therapy due to high leukocyte and thrombocyte counts

            -as palliative care in patients in blastic phase with leucocytosis and thrombocytosis

  • cancer of the cervix in conjunction with radiotherapy.

 

Entry checked: July 2025

08.01.05 Imatinab
08.01.05 Ipilimumab
08.01.05 Mitotane
08.01.05 Panitumumab
08.01.05 Pentostatin
08.01.05 Platinum compounds
08.01.05 Porfimer sodium and temoporfin
08.01.05 Procarbazine
08.01.05 Protein kinase inhibitors
08.01.05 Taxanes
08.01.05 Topoisomerase I inhibitors
08.01.05 Trabectedin
08.01.05 Trastuzumab
08.01.05 Tretinoin
08.01.05 Vismodegib
Classifications
May be initiated in any care setting
Specialist to advise therapy and provide first 28 days supply, continuation in Primary Care
Specialist to initiate and stabilise medicine prior to continuation in Primary Care
To be prescribed as per Shared Care Guidance. If no SCG in place status reverts to red.
Red medicines are designated as specialist only medicines which should only be prescribed by a specialist, usually within secondary care (either due to the requirement for specialist knowledge, long-term monitoring requirements, or restrictions that mean medicine supplies are only available to hospitals).
A decision has been made either locally and/or nationally not to routinely commission this preparation. Do not prescribe.
To be purchased over the counter. May be prescribed for chronic, long term conditions or on admission to hospital if essential.