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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary Chapter: 9 - Nutrition and blood 
Notes:

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing
Links:
BLMK ICB: Oral nutritional supplements guidance Vitamin and Mineral Supplementation Post Bariatric Surgery Guideline
09.01.06 Drugs used in neutropenia
NICE CG39: Anaemia management in chronic kidney disease

Filgrastim (Neupogen®)

RED
Restricted Drug Restricted
Paediatrics only
30 Mega Unit 0.3mg/1mL Injection
0.6mg/1mL & 300microgram/0.5mL Injection
BNF BNFc SPC

Filgrastim (Zarzio®)
(Pre-filled syringe)

RED
Restricted Drug Restricted

Consultant recommendation for licensed indications.

Up to 85kg: 30 million-units (300micrograms) pre-filled syringe

If > 85kg use: 48 million-units (480micrograms) pre-filled syringe

BNF BNFc SPC

Lenograstim (Granocyte®)

RED
Restricted Drug Restricted

Consultant recommendation only 
13.4 million-units (105 micrograms)
33.6 million-units (263 micrograms)

BNF BNFc SPC

Pegfilgrastim / Pegfilgrastim Biosimilar
(Solution for injection)

RED
Formulary

2nd line agent for treatment of neutropenia - restricted to adult patients allergic or intolerant to filgrastim.

Biologic drug. Prescribe by brand name. 

The biosimilar brand Pelgraz® is preferred for prescribing and initiation in all new adult patients.

NOTE: Pegfilgrastim (Neulasta®) and other pegfilgrastim biosimilar brands (e.g Pelmeg®) will be only be ordered if a patient is admitted on it.

October 2025 DTC

BNF BNFc SPC
Classifications
GREEN
May be initiated in any care setting
Amber SPA
Specialist to advise therapy and provide first 28 days supply, continuation in Primary Care
Amber SPIS
Specialist to initiate and stabilise medicine prior to continuation in Primary Care
SCG
To be prescribed as per Shared Care Guidance. If no SCG in place status reverts to red.
RED
Red medicines are designated as specialist only medicines which should only be prescribed by a specialist, usually within secondary care (either due to the requirement for specialist knowledge, long-term monitoring requirements, or restrictions that mean medicine supplies are only available to hospitals).
DNP
A decision has been made either locally and/or nationally not to routinely commission this preparation. Do not prescribe.
SELF
To be purchased over the counter. May be prescribed for chronic, long term conditions or on admission to hospital if essential.