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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary Chapter: 9 - Nutrition and blood 
Notes:

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing

09.06.04 Vitamin D

Colextra D3® (Colecalciferol 20,000 unit)
(Capsules)

First Choice

Refer to the Prescribing Guidelines below for a guide to dosing for treatment and prevention in adults and children.

For the treatment of vitamin D deficiency (serum vitamin D level <25 nmol/L) with a high dose/loading course regime:

Adult dosage: 2 capsules once weekly, for 7 weeks

Entry reviewed: October 2025

Colextra® (Colecalciferol 800 units)
(Capsules)

First Choice

800units = 20micrograms

Entry reviewed May 2025 

InVita D3® (Colecalciferol 50,000 units/1ml )
(Oral solution unit dose ampoules sugar free)

Second Choice

Refer to the Prescribing Guidelines below for a guide to dosing for treatment and prevention in adults and children.

If the patient has a swallowing difficulty or is a vegetarian.

For the treatment of vitamin D deficiency (serum vitamin D level 

Adult dosage: 1ml once weekly, for 6 weeks

Entry reviewed: October 2025

Stexerol D3® (Colecalciferol 1000 unit)
(Tablets)

Second Choice

 

Entry reviewed: May 2025

 

Calcifediol 266 microgram capsules (Domnisol®)

Formulary

Adult dosage: One capsule a month for the treatment or prevention of vitamin D deficiency or an adjunct in osteoporosis in patients with or at risk of deficiency.

First line for those with impaired hepatic function (alanine transaminase (ALT) aspartate aminotransferase (AST) are twice the upper limit of normal), malabsorption, or obesity.  

Second line option when adherence is poor or when patients are unable to become replete with first line options.

Entry reviewed: August 2024

Colecalciferol 10,000 units/ml
(Oral Drops (10mL))

Restricted Drug Restricted

For Paediatric patients only

Refer to the joint prescribing guidelines below for a guide to dosing for treatment and prevention in children.

Colecalciferol 3,000 units/ml liquid

RED
Restricted Drug Restricted

[Update Feb 2025]

As per EoE vitamins guideline. For use in NICU.

 

Desunin® (Colecalciferol 4000 units)
(Tablets)

Formulary

When a higher maintenance dose is required as advised by a specialist.

Ergocalciferol
(Intramuscular Injection)

RED
Restricted Drug Restricted

7.5mg/1mL (300,000 unit) Injection

Only prescribe when patients unable to take or comply with oral treatment. Refer to the joint prescribing guidelines below for a guide to dosing for treatment and prevention in adults and children.

Shortage until April 2025 in the interim use colecalciferol IM.

[Update Jan 2025]

Alfacalcidol

RED
Formulary
1microgram/0.5mL Injection

Alfacalcidol (One-Alpha®)

Formulary
0.25microgram & 1microgram Capsules
2microgram/1mL Oral Liquid

Calcitriol 250nanograms, 500nanograms
(Capsules)

Restricted Drug Restricted

For renal patients only.

Colecalciferol and Calcium Carbonate
(Chewable tablets)

Formulary

Hospital contract brands will be supplied in secondary care. Currently Adcal D3 - contains: colecalciferol 400 units / calcium carbonate 1.5g (500mg calcium)

Primary care, first line chewable once daily tablet options:

Calci-D,

Accrete D3 One a Day,

TheiCal-D3.

Most cost effective brands to be advised via OptimiseRx

Entry reviewed March 2025

Colecalciferol and Calcium Carbonate
(Effervescent tablets)

Restricted Drug Restricted

For swallowing difficulties and enteral feeding tube administration only.

Hospital contract brands will be supplied in secondary care. Currently Adcal D3 Dissolve - contains: colecalciferol 400 units / calcium carbonate 1.5g (500mg calcium)

Primary care options:

Adcal-D3 Dissolve, One effervescent tablet contains approximately 42.03mg of sodium.

Cacit D3 Dissolve. One sachet contains a total of 5mg of sodium.

Most cost effective brands to be advised via OptimiseRx

Entry reviewed July 2025

Colecalciferol and Calcium Carbonate
(Film coated, non-chewable tablets)

Restricted Drug Restricted

Hospital contract brands will be supplied in secondary care.

Primary care, non-chewable options:

Accrete D3,

Adcal-D3.

Most cost effective brands to be advised via OptimiseRx

Entry reviewed March 2025

Colecalciferol IM Injection
(300,000 units)

RED
Restricted Drug Restricted

Interim formulary status whilst shortage of Ergocalciferol IM. 

[Update Jan 2025]

Used only in exceptional circumstances  

Non formulary items

Calcium and Ergocalciferol (Calcium and vitamin D Tablets)

 
Non Formulary

Calcium lactate pentahydrate 300mg / calcium phosphate 150mg
(equivalent to 100mg elemental calcium) PLUS ergocalciferol 10micrograms (400 units).

No longer recommended

Colecalciferol (Kalcipos-D®)

 
Non Formulary

Colecalciferol 1,000 units (Sunvit D3®)

 
Non Formulary

Colecalciferol 25,000 unit liquid (Invita D3® )

 
Non Formulary

Colecalciferol 3200 unit capsules (Fultium D3®)

 
Non Formulary

Colecalciferol 400 units (Tablets)

Non Formulary

400units = 10micrograms

National and local guidance advises that everyone living in the UK should take at least 400units of vitamin D daily. This will be continued in hospital if patients own not available but patients must purchase on discharge. This is a food supplement.

In Primary Care - self-care, purchase OTC. Not to be prescribed.

Colecalciferol and Calcium Carbonate (Calcichew-D3 Once Daily)

 
Non Formulary

Colecalciferol and Calcium Carbonate (Calcichew-D3® Forte)

 
Non Formulary

E-D3® (colecalciferol preparations)

DNP
Non Formulary

High-cost preparations

 

Entry reviewed: November 2023

Paricalcitol (Zemplar®)

 
Non Formulary
Classifications
May be initiated in any care setting
Specialist to advise therapy and provide first 28 days supply, continuation in Primary Care
Specialist to initiate and stabilise medicine prior to continuation in Primary Care
To be prescribed as per Shared Care Guidance. If no SCG in place status reverts to red.
Red medicines are designated as specialist only medicines which should only be prescribed by a specialist, usually within secondary care (either due to the requirement for specialist knowledge, long-term monitoring requirements, or restrictions that mean medicine supplies are only available to hospitals).
A decision has been made either locally and/or nationally not to routinely commission this preparation. Do not prescribe.
To be purchased over the counter. May be prescribed for chronic, long term conditions or on admission to hospital if essential.