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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary Chapter: 9 - Nutrition and blood 
Notes:

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing

09.06.06 Vitamin K

Menadiol Sodium Phosphate

Formulary
10mg Tablets
Water soluble preparation for vitamin K and to be used in patients with hepatic disease

For ORAL treatment of elevated INR phytomenadione injection 2mg/0.2mL (Konakion MM Paediatric, licensed for this route) should be prescribed and administered via the ORAL route. For 10mg doses, the adult phytomenadione injection (10mg/mL) has been given orally. This is off-label but has been checked with the manufacturer. The formulation is the same as the paediatric konakion MM.

Phytomenadione
(Injection)

RED
Formulary

10mg/1mL Injection


May be administered by slow intravenous injection or by intravenous infusion. NOT for intramuscular injection. 

Prescriptions should be for the generic product phytomenadione 10mg/mL solution for injection, not the branded product

This has also been given orally but is off-label. For oral doses less than 10mg prescribe phytomenadione 2mg/0.2mL solution for injection.

 

Phytomenadione
(Injection)

Formulary

2mg/0.2mL Injection

BNF states: may be administered by mouth, or by intramuscular injection or by intravenous injection

The Konakion® MM Paediatric brand that was previously used has now been discontinued; only the generic phytomenadione is available. Prescriptions should therefore be for the generic product phytomenadione 2mg/0.2ml solution for injection, not the branded product.

Classifications
May be initiated in any care setting
Specialist to advise therapy and provide first 28 days supply, continuation in Primary Care
Specialist to initiate and stabilise medicine prior to continuation in Primary Care
To be prescribed as per Shared Care Guidance. If no SCG in place status reverts to red.
Red medicines are designated as specialist only medicines which should only be prescribed by a specialist, usually within secondary care (either due to the requirement for specialist knowledge, long-term monitoring requirements, or restrictions that mean medicine supplies are only available to hospitals).
A decision has been made either locally and/or nationally not to routinely commission this preparation. Do not prescribe.
To be purchased over the counter. May be prescribed for chronic, long term conditions or on admission to hospital if essential.