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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary Chapter: 11 - Eye 
Notes:

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing

11.08.02 Ocular diagnostic and peri-operative preparations and photodynamic treatment
11.08.02 Ocular diagnostic preparations
11.08.02 Ocular peri-operative drugs
11.08.02 Subfoveal choroidal neovascularisation

Aflibercept 40mg/1mL (Yesafili®)
(Intravitreal Injection )

RED
Second Choice

FOR ALL PRESCRIBING – Blueteq or High cost drug form required – see link from Formulary homepage. 

Restricted - prescribing by consultant Ophthalmologists in-line with NICE TA's below.

Use biosimilar brand Yesafili® 1st line - Eylea® (originator brand) to be used for patients who cannot switch to biosimilar.

 

Entry reviewed: November 2025

Aflibercept 114.3 mg/1 ml (equiv. to 8mg) (Eylea®)
(Intravitreal Injection )

RED
Formulary

FOR ALL PRESCRIBING – Blueteq or High cost drug form required – see link from Formulary homepage. 

Restricted - prescribing by consultant Ophthalmologists in-line with NICE TA's below.

Bevacizumab gamma (Lytenava®)
(25 mg/mL solution for injection)

RED
Restricted Drug Restricted

FOR ALL PRESCRIBING - Blueteq or High Cost Drug form required - see link on Formulary Home page.

Restricted - prescribing by Consultant Ophthalmologists in line with the following NICE TA(s):

Bevacizumab intravitreal 1.25mg in 0.05mL (Avastin®)
(Injection)

RED
Restricted Drug Restricted

Approved for the treatment of retinopathy of prematurity.

Brolucizumab (Beovu®)
(120 mg/ml solution for injection in pre-filled syringe)

RED
Restricted Drug Restricted

FOR ALL PRESCRIBING - Blueteq or High Cost Drug form required - see link on Formulary Home page.

Restricted - prescribing by Consultatnt Ophthalmologist in line with the following NICE TA(s)

Faricimab (Vabysmo ®)

RED
Restricted Drug Restricted

120 mg/mL solution for injection

120 mg/mL solution for injection in prefilled syringe

FOR ALL PRESCRIBING – Blueteq or High cost drug form required – see link from Formulary homepage. 

Restricted - prescribing by consultant Ophthalmologists in accordance with the following NICE TAs:

Ranibizumab 10mg/ml intravitreal injection
(Intravitreal Injection )

RED
Restricted Drug Restricted

Biosimilar brand(s): Ongavia®, Ximluci® (preferred)

Originator brand: Lucentis®

 

FOR ALL PRESCRIBING – Blueteq or High cost drug form required – see link from Formulary homepage.

Restricted - prescribing by consultant Ophthalmologists:

1. For the treatment of age related macular degeneration in accordance with NICE TA155.
2. For treating diabetic macular oedema in accordance with NICE TA274.

3. For Central Retinal Vein Occlusion in accordance with NICE TA283

4. For treatment of visual impairment due to choroidal neovascularisation (CNV) secondary to pathologic myopia in accordance with NICE TA 298.

Entry reviewed: November 2023

Verteporfin (Visudyne®)
(Intravenous infusion)

RED
Restricted Drug Restricted
FOR ALL PRESCRIBING – Blueteq or High cost drug form required – see link from Formulary homepage.

JPC Recommendations:
 To support the use of PDT with verteporfin for the treatment of Chronic Central Serous Retinopathy.
 Approval is subject to patient outcomes being provided (via Blueteq reauthorisation process).
Non formulary items

Pegaptanib Sodium (Macugen®)

 
Non Formulary
Not recommended by NICE.
11.08.02 Vitreomacular traction
Classifications
May be initiated in any care setting
Specialist to advise therapy and provide first 28 days supply, continuation in Primary Care
Specialist to initiate and stabilise medicine prior to continuation in Primary Care
To be prescribed as per Shared Care Guidance. If no SCG in place status reverts to red.
Red medicines are designated as specialist only medicines which should only be prescribed by a specialist, usually within secondary care (either due to the requirement for specialist knowledge, long-term monitoring requirements, or restrictions that mean medicine supplies are only available to hospitals).
A decision has been made either locally and/or nationally not to routinely commission this preparation. Do not prescribe.
To be purchased over the counter. May be prescribed for chronic, long term conditions or on admission to hospital if essential.