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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary Chapter: 4 - Central nervous system 
Notes:

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing

04.09.01 Dopaminergic drugs used in Parkinsons disease
04.09.01 Dopamine receptor agonists
04.09.01 Levodopa
04.09.01 Monoamine-oxidase-B inhibitors

Safinamide tablets (Xadago®)

Second Choice

50mg and 100mg film-coated tablets

When first line monoamine oxidase B inhibitors are ineffective or are not tolerated.

Entry reviewed July 2025

Rasagiline 1mg
(Tablets)

Formulary

Selegiline 5mg, 10mg
(Tablets)

Formulary
04.09.01 Catachol-O-methyltransferase inhibitors
04.09.01 Amantadine
Classifications
May be initiated in any care setting
Specialist to advise therapy and provide first 28 days supply, continuation in Primary Care
Specialist to initiate and stabilise medicine prior to continuation in Primary Care
To be prescribed as per Shared Care Guidance. If no SCG in place status reverts to red.
Red medicines are designated as specialist only medicines which should only be prescribed by a specialist, usually within secondary care (either due to the requirement for specialist knowledge, long-term monitoring requirements, or restrictions that mean medicine supplies are only available to hospitals).
A decision has been made either locally and/or nationally not to routinely commission this preparation. Do not prescribe.
To be purchased over the counter. May be prescribed for chronic, long term conditions or on admission to hospital if essential.