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Bedfordshire and Luton Joint Formulary
Bedfordshire Hospitals NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes ICB
Formulary Chapter: 5 - Infections 
Notes:

For full details on UKHSA guidance for managing common infections with local amendments please see:

BLMK Primary Care Antimicrobial Guidelines hosted via: https://blmkantibioticspubliclive.azurewebsites.net/

Secondary care antimicrobial guidelines:

Bedfordshire Hospitals Foundation Trust: Antimicrobial guidelines are hosted on:  EOLAS Medical App. 
05.03.01 HIV infection
All prescribing for HIV patients should be in line with current BHIVA guidelines
05.03.01 Nucleoside reverse transcriptase inhibitors

Abacavir (Ziagen®)

RED
Restricted Drug Restricted

300mg Tablets
100mg/5mL Solution

Restricted - must be prescribed by HIV consultants only

NHSE Commissioned medicine - No prescribing in Primary Care

BNF BNFc SPC

Abacavir and Lamivudine

RED
Restricted Drug Restricted
Restricted - must be prescribed by HIV consultants only

Abacavir 600mg/Lamivudine 300mg Film Coated Tablets
BNF BNFc SPC

Abacavir and Lamivudine and Zidovudine (Trizivir®)

RED
Restricted Drug Restricted
Abacavir 300mg/Lamivuidine 150mg/Zidovudine 300mg

Restricted - must be prescribed by HIV consultants only
BNF BNFc SPC

Lamivudine

RED
Restricted Drug Restricted

Restricted

For HIV and Hepatitis B 

100mg, 150mg & 300mg Tablets
100mg Film Coated Tablets
10mg/1mL Solution

BNF BNFc SPC

Tenofovir Disproxil (Viread®)

RED
Restricted Drug Restricted

245mg Tablets : Restricted - must be prescribed by Consultant Hepatologist for the treatment of Chronic hepatitis B in accordance with NICE TA173.

204mg tablets in combination with other antiretrovirals: To be prescribed by HIV consultants only.

BNF BNFc SPC
NICE CG165: Hepatitis B (chronic) - incorporates TA173 NICE TA173: Hepatitis B (chronic) - tenofovir disoproxil

Tenofovir 245mg, Efavirenz 600mg and Emtricitabine 200mg (Atripla®)

RED
Restricted Drug Restricted
Efavirenz 600mg/Emtricitabine 200mg/Tenofovir Disoproxil
245mg

Prescribe as Truvada PLUS generic efavirenz where possible.

Restricted - must be prescribed by HIV consultants only
BNF BNFc SPC

Tenofovir Alafenamide and Emtricitabine (Descovy®)

RED
Restricted Drug Restricted

Restricted - must be prescribed by HIV consultants only

Emtricitabine 200mg/Tenofovir Alafenamide 10mg Tablets

Emtricitabine 200mg/Tenofovir Alafenamide 25mg Tablets

BNF BNFc SPC
Department Of Health (April 2015) - EAGA guidance on HIV post-exposure prophylaxis

Tenofovir Disproxil and Emtricitabine (Truvada®)

RED
Restricted Drug Restricted

Restricted - must be prescribed by HIV consultants only

Emtricitabine 200mg/Tenofovir Disproxil 245mg Tablets

BNF BNFc SPC
Department Of Health (April 2015) - EAGA guidance on HIV post-exposure prophylaxis

Tenofovir, cobicistat, elvitegravir & emtricitabine (Stribild®)

RED
Restricted Drug Restricted
Restricted - prescribing by HIV Consultants only in accordance with BHIVA guidelines.

Contains Tenofovir 245mg/Cobicistat 150mg/Elvitegravir 150mg/Emtricitabine 200mg Tablets
BNF BNFc SPC

Zidovudine and lamivudine

RED
Restricted Drug Restricted
Restricted - prescribing by HIV Consultants only.

Zidovudine 300mg / lamivudine 150mg
BNF BNFc SPC

Emtricitabine 200mg, Rilpivirine 25mg and Tenofovir Alafenamide 25mg (Odefsey®)

RED
Restricted Drug Restricted

Emtricitabine 200mg/Rilpivirine 25mg/Tenofovir Alafenamide 25mg

Restricted - must be prescribed by HIV Consultants only

BNF BNFc SPC

Zidovudine

RED
Restricted Drug Restricted

Restricted - must be prescribed by HIV Consultants only

100mg Capsules

250mg Capsules


50mg/5mL Syrup
10mg/ml oral solution sugar free

200mg/20mL Injection

BNF BNFc SPC
05.03.01 Protease inhibitors
05.03.01 Non-nucleoside reverse transcriptase inhibitors
05.03.01 Other antiretrovirals
05.03.01 Pharmacokinetic enhancers of antiretrovirals
Classifications
GREEN
May be initiated in any care setting
Amber SPA
Specialist to advise therapy and provide first 28 days supply, continuation in Primary Care
Amber SPIS
Specialist to initiate and stabilise medicine prior to continuation in Primary Care
SCG
To be prescribed as per Shared Care Guidance. If no SCG in place status reverts to red.
RED
Red medicines are designated as specialist only medicines which should only be prescribed by a specialist, usually within secondary care (either due to the requirement for specialist knowledge, long-term monitoring requirements, or restrictions that mean medicine supplies are only available to hospitals).
DNP
A decision has been made either locally and/or nationally not to routinely commission this preparation. Do not prescribe.
SELF
To be purchased over the counter. May be prescribed for chronic, long term conditions or on admission to hospital if essential.